Scientists from the United States figured out how to lose weight using antibodies
'09.11.2020'
Source: Obozrevatel
In the United States, scientists have developed an antibody-based drug, a single injection of which improves metabolism and helps to lose extra pounds. Obozrevatel.
So, for the purpose of losing weight, the researchers suggested using the long-acting antibody BFKB8488A. The results of the work were published by the journal Proceedings of the National Academy of Sciences of the United States of America.
Thus, a study in monkeys showed that this antibody mimics the effect of the hormone FGF21, which is produced in the cells of adipose tissue and the pancreas, regulates metabolism, energy expenditure and feeding behavior.
Scientists have also tested the antibodies in humans. The experiment involved 60 overweight volunteers. As it turned out, a single subcutaneous injection of the BFKB8488A antibody resulted in an improvement in metabolism that lasted up to 60 days.
On the same diet, the participants who received the antibody recorded a 1,20 kilogram weight loss compared to 0,28 kilograms in the placebo group.
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In addition, they showed a rejection of sweet food, an improvement in cardiometabolic parameters, and a decrease in carbohydrate intake.
At this stage, the researchers plan to continue testing, although it is already clear that the effect of BFKB8488A is able to adjust metabolism in overweight people and alter their eating behavior.
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