The article has been automatically translated into English by Google Translate from Russian and has not been edited.

San Francisco startup reveals the secret of eternal youth

'31.08.2017'

Source: New Atlas

A young startup Ambrosia, which was founded in 2016, is about to begin an interesting clinical study, which will be based on the possibility of using blood transfusions to rejuvenate the body. He writes about it New Atlas.

Photo: depositphotos

The idea that with the help of blood transfusion it is possible to rejuvenate the body is not new. Alchemists, scientists and researchers have been trying to prove this fact since the 16 century.

German chemist Andreas Libavy proposed to connect the arteries of a young and elderly man.

"The hot and strong blood of a young man will flow into the old one, as if it were a source of youth, and all his weakness will dissipate," wrote Libavius.

In the 16 century, no one had any idea about the complexity of the circulatory system. This became known only at the beginning of the 20 century.

In 1920, the philosopher and doctor Alexander Bogdanov did not find anyone who wanted to experiment, and therefore tried the method of blood transfusion on himself. He claimed that in this way he improved his eyesight, slowed down the process of hair loss and got a surge of energy.

However, it was the experiments on themselves and destroyed Bogdanov. A few years after the start of the experiments, he died. Supposedly, along with someone else's blood, he infected himself with malaria or tuberculosis. According to other sources, he infused himself with an incompatible blood group.

In 2014, Stanford University published a study that described experiments on mice. From the blood of young mice, they isolated plasma and injected it into old mice.
The results were impressive. Observation of old mice showed that their behavior has changed. They became livelier and more energetic.

Study originally rejected by journal Naturewas eventually published in Nature Medicine titled "Young blood changes age-related impairments in cognitive function and synoptic plasticity in mice."

Photo: depositphotos

Young entrepreneur and scientist Jesse Karmazin was inspired by all this research and founded the company Ambrosiawhich will provide its services through a patient-funded clinical trial that has already received formal registration with the US National Institutes of Health. Clinical trials will take place over two years.

Anyone older than 35 can become a participant in the test and who is ready to pay 8 000 dollars per procedure.

The test will include a study of a specific set of age-related biomarkers from each patient before the experiment and one month after treatment.

Many scientists have already criticized the clinical research Ambrosia uses to provide its services. They argue that due to the lack of a placebo control group, ambiguity regarding volunteers regarding the age of biomarkers and the problem of funding by the patients themselves, the result may be erroneous.

Interestingly, one of the skeptics who opposed such an experiment was Stanford neuroscientist Tony Vis-Korai, who was a participant in an experiment with mice.

“People want to believe that young blood has a rejuvenating effect, although we do not have evidence that this method works in humans, and we do not understand the mechanism of how this happens in mice. Interest in this topic is fueled by stories about vampires, not otherwise, ”said Vis-Koray.

But despite the criticism, 600 people were registered to participate in the Ambrosia experiment. The average age of volunteers is 60 years.

A course of rejuvenation costs 8 000 dollars and includes 1,5 liters of plasma, poured into a person for two days. The source of the raw material is the blood bank, from which the red blood cells are removed, and then the plasma extracted from it is transferred to the patient.

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